Polycystic ovary syndrome (PCOS) is a multifaceted condition characterized by chronic anovulation and excess ovarian activity, in contrast to other causes of anovulation that involve ovarian dormancy or primary insufficiency. Recent studies indicated that Polycystic ovary syndrome is associated with low-grade chronic inflammation and that women with PCOS are at increased risk of non-alcoholic fatty liver disease. The inflammatory and metabolic derangements associated with PCOS are explained in part by the coexistence of insulin resistance and obesity but are further fueled by the androgen excess. New insights into the regulation of hormones and cytokines in muscle and fat tissue support the concept that PCOS is a systemic syndrome. The therapeutic plan should be tailored to the patient phenotype, complaints, and reproductive desire. Of note, the aromatase inhibitor letrozole seems to be more effective than the reference drug clomiphene citrate to treat infertility due to PCOS. Integral management by a multidisciplinary team may help the patients to adhere to lifestyle interventions and thereby reduce body adiposity and recover their metabolic and reproductive health.
Regular exercise confers significant benefits for health and wellness. National guidelines from the US Department of Health and Human Services (HHS) and the American College of Obstetrics and Gynecology (ACOG) advise that all healthy pregnant women should engage routinely in exercise, after consultation with a care provider.1,2 Exercise is safe and beneficial for most pregnant women and their fetuses, within parameters as described by expert consensus as summarized by the ACOG Committee Opinion and other expert guidance.
Objetivos: Valorar la precisión de la determinación ecográfíca del sexo fetal entre las 11 y las 14 semanas
en una cohorte no seleccionada de gestantes.